Sensi-Care

Generic Name: topical emollients (TOP i kal ee MOL i ents)

Brand Names: Aloe Vesta Cream, AlphaSoft, AmeriPhor, Aqua Glycolic, Aqua Lube, Aquaphor, Aveeno, Baby Lotion, Baby Oil, Bag Balm, Baza-Pro, Beta Care, Blistex Lip Balm, Carmex, CarraKlenz, CeraVe, CeraVe AM, Cetaphil Lotion, Chap Stick, Citraderm, CoolBottoms, Corn Huskers Lotion, Curel Moisture Lotion, Derma Soothe, Dr Scholl's Essentials Cracked Skin Repair, Eucerin, Herpecin-L, K-Y Jelly, Keri Lotion, Lamisilk Heel Balm, Lubri-Soft, Lubriderm, Mederma, Moisturel, Natural Ice, NeutrapHor, NeutrapHorus Rex, Neutrogena Cleansing, Neutrogena Lotion, Nivea, Nutraderm, Pacquin, Phisoderm, Pretty Feet & Hands, Proshield Skincare Kit, Remedy 4-in-1 Cleansing Lotion, Replens, Secura, Sensi-Care, Soft Sense, St. Ives, Theraplex Lotion, Vaseline Intensive Care

What are Sensi-Care (topical emollients)?

Emollients are substances that moisten and soften your skin.

Topical (for the skin) emollients are used to treat or prevent dry skin. Topical emollients are sometimes contained in products that also treat acne, chapped lips, diaper rash, cold sores, or other minor skin irritation.

There are many brands and forms of topical emollients available and not all are listed on this leaflet.

Topical emollients may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Sensi-Care (topical emollients)?

You should not use a topical emollient if you are allergic to it. Topical emollients will not treat or prevent a skin infection.

Ask a doctor or pharmacist before using this medication if you have deep wounds or open sores, swelling, warmth, redness, oozing, bleeding, large areas of skin irritation, or any type of allergy.

What should I discuss with my healthcare provider before using Sensi-Care (topical emollients)?

You should not use a topical emollient if you are allergic to it. Topical emollients will not treat or prevent a skin infection.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have:

• 
  

  deep wounds or open sores;

  
  


• 
  

  swelling, warmth, redness, oozing, or bleeding;

  
  


• 
  

  large areas of skin irritation;

  
  


• 
  

  any type of allergy; or

  
  


• if you are pregnant or breast-feeding.

How should I use Sensi-Care (topical emollients)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Clean the skin where you will apply the topical emollient. It may help to apply this product when your skin is wet or damp. Follow directions on the product label.

Shake the product container if recommended on the label.

Apply a small amount of topical emollient to the affected area and rub in gently.

If you are using a stick, pad, or soap form of topical emollient, follow directions for use on the product label.

Do not use this product over large area of skin. Do not apply a topical emollient to a deep puncture wound or severe burn without medical advice.

If your skin appears white or gray and feels soggy, you may be applying too much topical emollient or using it too often.

Some forms of topical emollient may be flammable and should not be used near high heat or open flame, or applied while you are smoking.

Store as directed away from moisture, heat, and light. Keep the bottle, tube, or other container tightly closed when not in use.

What happens if I miss a dose?

Since this product is used as needed, it does not have a daily dosing schedule. Seek medical advice if your condition does not improve after using a topical emollient.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Sensi-Care (topical emollients)?

Avoid getting topical emollients in your eyes, nose, or mouth. If this does happen, rinse with water. Avoid exposure to sunlight or tanning beds. Some topical emollients can make your skin more sensitive to sunlight or UV rays.

Sensi-Care (topical emollients) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using the topical emollient and call your doctor if you have severe burning, stinging, redness, or irritation where the product was applied.

Less serious side effects are more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Sensi-Care (topical emollients)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied products. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Sensi-Care resources

• Sensi-Care Use in Pregnancy & Breastfeeding
• Sensi-Care Support Group
• 0 Reviews for Sensi-Care - Add your own review/rating

• Biafine Emulsion MedFacts Consumer Leaflet (Wolters Kluwer)


• Campath Monograph (AHFS DI)


• Campral Monograph (AHFS DI)


• Camptosar Monograph (AHFS DI)


• Diabinese Monograph (AHFS DI)


• Kinerase Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Neosalus Foam MedFacts Consumer Leaflet (Wolters Kluwer)


• Promiseb Cream MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Sensi-Care with other medications

• Dry Skin

Where can I get more information?

• Your pharmacist can provide more information about topical emollients.

Septra

Pronunciation: SUL-fa-meth-OX-a-zole/trye-METH-oh-prim
Generic Name: Sulfamethoxazole/Trimethoprim
Brand Name: Examples include Bactrim and Septra

Septra is used for:

Treating infections caused by certain bacteria.

Septra is an antibiotic combination containing a sulfonamide antibiotic. It works by killing sensitive bacteria.

Do NOT use Septra if:

• you are allergic to any ingredient in Septra or to similar medicines


• you had a severe allergic reaction to any other sulfonamide (sulfa) medicine (eg, glipizide, hydrochlorothiazide)


• you are taking dofetilide


• you have anemia caused by low levels of folate in the blood


• you are in week 38 of pregnancy or later (full-term) or you are breast-feeding


• the patient is a child younger than 2 months old


• you will be receiving a live oral typhoid vaccine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Septra:

Some medical conditions may interact with Septra. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription (especially seizure medications) or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have liver or kidney problems, blood problems (eg, anemia, porphyria), asthma, or HIV infection


• if you have severe allergies, glucose-6-phosphate dehydrogenase deficiency, or an enzyme deficiency


• if you are at risk for low levels of folate in the blood (eg, you have alcoholism, you are elderly, you do not absorb nutrients from food properly, you are in a poor nutritional state, you are taking medicine for seizures)

Some MEDICINES MAY INTERACT with Septra. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Leucovorin because it may decrease Septra's effectiveness


• Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) or diuretics (eg, hydrochlorothiazide) because they may increase the risk of Septra's side effects


• Anticoagulants (eg, warfarin) because the risk of bleeding may be increased


• Dofetilide because the risk of severe heart problems may be increased


• Digoxin, methotrexate, phenytoin, sulfones (eg, dapsone), or sulfonylureas (eg, glipizide) because the risk of their side effects may be increased by Septra


• BCG vaccine or oral typhoid vaccine because their effectiveness may be decreased by Septra


• Cyclosporine because its effectiveness may be decreased and the risk of liver side effects may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Septra may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Septra:

Use Septra as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Septra by mouth with or without food.


• Septra works best if it is taken at the same time each day.


• Take Septra with a full glass of water (8 oz/240 mL). Drinking extra fluids while you are taking Septra is recommended. Check with your doctor for instructions.


• To clear up your infection completely, take Septra for the full course of treatment. Keep taking it even if you feel better in a few days.


• If you miss a dose of Septra, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Septra.

Important safety information:

• Septra may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Septra. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.


• Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.


• Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur during treatment or within several months after treatment with Septra. Do not treat diarrhea without first checking with your doctor.


• Be sure to use Septra for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.


• Septra only works against bacteria; it does not treat viral infections (eg, the common cold).


• Long-term or repeated use of Septra may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.


• Diabetes patients - Septra may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Septra may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Septra.


• Lab tests, including complete blood cell counts and kidney function, may be performed while you use Septra. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Septra with caution in the ELDERLY; they may be more sensitive to its effects, especially severe skin reactions, bone marrow suppression, or high blood potassium levels.


• Septra should not be used in CHILDREN younger than 2 months old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Septra while you are pregnant. Do not use Septra if you are in week 38 of pregnancy or later (full-term). Septra is found in breast milk. Do not breast-feed while taking Septra.

Possible side effects of Septra:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Appetite loss; diarrhea; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); blistered, peeling, red, or swollen skin; bloody or black, tarry stools; chest pain; chills, fever, or sore throat; confusion; dark urine; decreased urination; depression; hallucinations; irregular heartbeat; joint or muscle pain; mental or mood changes; painful or stiff neck; purple patches under the skin; seizures; severe diarrhea; severe or persistent cough; severe or persistent headache; severe or persistent nausea or vomiting; shortness of breath; stomach cramps/pain; unusual bruising or bleeding; unusual tiredness or weakness; unusually pale skin; vaginal irritation or discharge; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Septra side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blood in urine; confusion; depression; dizziness; drowsiness; loss of consciousness; severe nausea or vomiting; severe or prolonged headache; unusual bruising or bleeding.

Proper storage of Septra:

Store Septra at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Keep in a tight, light-resistant container. Do not store in the bathroom. Keep Septra out of the reach of children and away from pets.

General information:

• If you have any questions about Septra, please talk with your doctor, pharmacist, or other health care provider.


• Septra is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Septra. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Septra resources

• Septra Side Effects (in more detail)
• Septra Dosage
• Septra Use in Pregnancy & Breastfeeding
• Septra Drug Interactions
• Septra Support Group
• 6 Reviews for Septra - Add your own review/rating

• Septra Prescribing Information (FDA)


• Septra Consumer Overview


• Septra Advanced Consumer (Micromedex) - Includes Dosage Information


• Bactrim Consumer Overview


• Bactrim Prescribing Information (FDA)


• Bactrim DS Prescribing Information (FDA)


• Cotrim Consumer Overview

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Sensipar

Generic Name: cinacalcet (Oral route)

sin-a-KAL-set

Commonly used brand name(s)

In the U.S.

• Sensipar

Available Dosage Forms:

• Tablet

Therapeutic Class: Calcium Regulator

Pharmacologic Class: Calcimimetic

Uses For Sensipar

Cinacalcet is used to treat hyperparathyroidism in patients with chronic kidney disease who are on dialysis. Hyperparathyroidism is a condition that is caused when the parathyroid glands located in the neck make too much parathyroid hormone (PTH). This hormone helps to control the concentrations of calcium and phosphorus in your blood. Cinacalcet lowers the amount of PTH which lowers the calcium and phosphorus concentrations. Cinacalcet is also used to lower calcium in the blood of patients with parathyroid cancer.

This medicine is available only with your doctor's prescription.

Before Using Sensipar

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of cinacalcet in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cinacalcet in the elderly.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Clozapine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Amitriptyline


• Desipramine


• Itraconazole


• Ketoconazole

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Bone disease or


• Heart disease or


• Heart failure or


• Heart rhythm problems (e.g., arrhythmia) or


• Hypotension (low blood pressure) or


• Seizures, history of—Use with caution. May make these conditions worse.

• Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of Sensipar

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

It is best to take this medicine with food or shortly after a meal.

Swallow the tablet whole. Do not crush, break, or chew it.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets):
  
  • For hypercalcemia associated with parathyroid cancer:
    
    • Adults—At first, 30 milligrams (mg) two times a day. Your doctor may adjust your dose every 2 to 4 weeks.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  
  • For hyperparathyroidism with chronic kidney disease:
    
    • Adults—At first, 30 milligrams (mg) once a day. Your doctor may adjust your dose every 2 to 4 weeks.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Sensipar

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Do not take other medicines unless they have been discussed with your doctor. Taking other medicines together with cinacalcet may require your doctor to change the dose of one of the medicines or cinacalcet.

This medicine may lower the calcium in your blood. If you have any of these symptoms, check with your doctor right away: abdominal or stomach cramps; confusion; convulsions; difficulty with breathing; irregular heartbeats; mood or mental changes; muscle cramps in the hands, arms, feet, legs, or face; numbness and tingling around the mouth, fingertips, or feet; shortness of breath; or tremors.

Sensipar Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Blurred vision


• chest pain


• dizziness


• headache


• nervousness


• pounding in the ears


• slow or fast heartbeat

Less common

• Convulsions


• cough or hoarseness


• fever or chills


• loss of bladder control


• lower back or side pain


• muscle spasm or jerking of all extremities


• painful or difficult urination


• sudden loss of consciousness

Incidence not known

• Abdominal or stomach cramps


• confusion


• decreased urine output


• difficulty with breathing


• difficulty with moving


• dilated neck veins


• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


• extreme fatigue


• fainting


• irregular breathing


• irregular heartbeats


• joint pain


• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


• low bone turnover


• mood or mental changes


• muscle aching or cramping


• muscle cramps in the hands, arms, feet, legs, or face


• muscle pains or stiffness


• numbness and tingling around the mouth, fingertips, or feet


• shortness of breath


• sweating


• swelling of the face, fingers, feet, or lower legs


• swollen joints


• tightness in the chest


• tremor


• troubled breathing


• unusual tiredness or weakness


• weight gain


• wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Diarrhea


• lack or loss of strength


• loss of appetite


• nausea


• vomiting


• weight loss

Incidence not known

• Hives or welts


• itching


• rash


• redness of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Sensipar side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Sensipar resources

• Sensipar Side Effects (in more detail)
• Sensipar Dosage
• Sensipar Use in Pregnancy & Breastfeeding
• Drug Images
• Sensipar Drug Interactions
• Sensipar Support Group
• 3 Reviews for Sensipar - Add your own review/rating

• Sensipar Prescribing Information (FDA)


• Sensipar Monograph (AHFS DI)


• Sensipar MedFacts Consumer Leaflet (Wolters Kluwer)


• Sensipar Consumer Overview

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Sentry HC Dermasphere Medicated Shampoo

Dosage Form: FOR ANIMAL USE ONLY
Medicated Shampoo For Dogs

Indications and Usage for Sentry HC Dermasphere Medicated Shampoo

Sentry HC Dermasphere Medicated Shampoo For Dogs is an antiseborrheic shampoo that aids in the removal of scales, crust, and excessive skin oil associated with seborrhea and other non-specific skin conditions.  Combines the proven benefits of oatmeal, sulfur and salicylic acid.  Contains Dermaspheres, a micro encapsulation technology that holds key ingredients in miscroscopic spheres and improves th effectiveness of the shampoo.


SIGNS:  Recommended for dogs with oily skin and coat.

• Specially formulated for seborrhea and other skin conditions
  
  


• Medicated Dermaspheres attach to skin and coat and release over time
  
  


• Aids in the removal of scales, crust and excessive skin oil
  

DIRECTIONS FOR USE

Shake well before use.  Wet the hair coat with warm water.  Apply a thin line of shampoo from the base of the neck to the base of the tail.  Massage the shampoo into wet hair coat.  Rinse and repeat.  May be used two to three times a week.  Discontinue use and consult a veterinarian if undue skin irritation develops or increases, or if the condition persists or recurs, as symptoms may be indicative of an underlying serious condition.

CAUTION

For Animal Use Only.  FOR EXTERNAL USE ONLY.  Avoid contact with eyes or mucous membranes.  In case of contact, flush eyes with water and seek medical attention if irritation persists.

KEEP OUT OF REACH OF CHILDREN

Warnings

Wash hands after use.  In case if accidental ingestion, seek professional assistance or contact a Poison Control Center immediately.

ACTIVE INGREDIENTS

Salicylic Acid 2%, Solubilized Sulfur 2%.

OTHER INGREDIENTS

Water, Sodium Lauryl Sulfate, Lauramide DEA, Glycerin, Colloidal Oatmeal, Dermaspheres, Magnesium Aluminum Silicate, Sodium Hydroxide, Fragrance, Hydroxypropyl Cellulosa, FD and C Blue #1.  May also contain sodium chloride and/or sodium hydroxide.

How is Sentry HC Dermasphere Medicated Shampoo Supplied

Net 12 fl oz (354 mL)

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

Distributed by:  Sergeant's Pet Care Products, Inc., Omaha NE 68130


Made in USA


PATENTED DERMASPHERE TECHNOLOGY


Patent #6,277,404

Sentry HC Dermasphere Medicated Shampoo FOR DOGS  salicylic acid, solubilized sulfur  lotion/shampoo

Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 21091-074 Route of Administration TOPICAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength SALICYLIC ACID (SALICYLIC ACID) SALICYLIC ACID 7.08 mL  in 354 mL SULFUR (SULFUR) SULFUR 7.08 mL  in 354 mL

Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found

Product Characteristics Color blue (Aqua Blue) Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 21091-074-12 354 mL In 1 BOTTLE, PUMP None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
unapproved drug other		11/19/2008

Labeler - Sergeant's Pet Care Products, Inc. (876995171)

Revised: 04/2010Sergeant's Pet Care Products, Inc.

Sentry AQ Mardel Maracyn

Dosage Form: FOR ANIMAL USE ONLY
Medication for All Freshwater Fish - Fast Dissolving Powder Form

Indications and Usage for Sentry AQ Mardel Maracyn

For the treatment and control of body fungus "columnaris," fin and tail rot, popeye and gill disease in tetras, cichlids, livebearers, catfish and goldfish caused by Flavobacterium columnare, Haemophilus piscium, Aeromonus punctata, Aeromonus hydrophila and Cytophaga aquatilis bacteria.

Read enclosed brochure carefully before using.  Use of a hospital tank is recommended.  No water changes, pH or temperature adjustments necessary if readings are in ideal range.  Maintain normal filtration and air.

INSTRUCTIONS

Add the contents of one packet per 10 gallons of water and repeat every 24 hours for 5 days.  Repeat this 5 day treatment only once if needed.  Important: Treat for 5 days even if visible signs disappear.  May be used concurrently with Coppersafe, Maracide, Maracyn Two or Maroxy.  Refer to enclosed fish disease chart for proper combination use.

KEEP OUT OF REACH OF CHILDREN

For aquarium use only. THIS PRODUCT IS INTENDED FOR THE EXCLUSIVE USE WITH ORNAMENTAL FISH AND/OR OTHER ORNAMENTAL ORGANISMS AND IS NOT INTENDED FOR USE WITH HUMANS OR FISH FOR HUMAN CONSUMPTION.

ACTIVE INGREDIENT

Each packet contains 200 mg erythromycin activity.  Licensed under U.S. Patent 3,737,526.

How is Sentry AQ Mardel Maracyn Supplied

Net Contents:


  8-0.021 oz. (0.6 g) Powder Packets


24-0.021 oz. (0.6 g) Powder Packets

PACKAGING COMPONENT

Sentry AQ Mardel Maracyn


Distributed by:


Sergeant's Pet Care Products, Inc., Omaha, NE 68130


www.sentrypetcare.com

Sentry AQ Mardel Maracyn  erythromycin  powder

Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 21091-011 Route of Administration EXTRACORPOREAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength ERYTHROMYCIN PHOSPHATE (ERYTHROMYCIN) ERYTHROMYCIN PHOSPHATE 200 mg  in 0.6 g

Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 21091-011-08 8 PACKET In 1 CARTON contains a PACKET 1 0.6 g In 1 PACKET This package is contained within the CARTON (21091-011-08) 2 21091-011-24 24 PACKET In 1 CARTON contains a PACKET 2 0.6 g In 1 PACKET This package is contained within the CARTON (21091-011-24)

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
unapproved drug other		02/06/2009

Labeler - Sergeant's Pet Care Products, Inc. (876995171)

Revised: 12/2009Sergeant's Pet Care Products, Inc.

SenoSol-X

Generic Name: senna (SEN nah)

Brand Names: Black Draught, Dr Caldwell Laxative, Ex-Lax Chocolated, Ex-Lax Maximum Relief Formula, Ex-Lax Regular Strength Pills, Fletchers Castoria, Innerclean, Pedia-Lax, Perdiem Overnight, Senexon, Senna, Senna Lax, Senna Smooth, Senna Soft, Senna-gen, Senokot, Senokot Extra, SenokotXTRA, SenoSol, SenoSol-X

What is SenoSol-X (senna)?

Senna is also known as Cassia senna, tinnevelly senna, India senna, Alexandrian senna, and Khartoum senna.

Senna has been used in alternative medicine as an aid to treat constipation.

Not all uses for senna have been approved by the FDA. Senna should not be used in place of medication prescribed for you by your doctor.

Senna is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Senna may also be used for other purposes not listed in this product guide.

What is the most important information I should know about SenoSol-X (senna)?

Not all uses for senna have been approved by the FDA. Senna should not be used in place of medication prescribed for you by your doctor.

Senna is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Use senna as directed on the label, or as your healthcare provider has prescribed. Do not use this product in larger amounts or for longer than recommended.

Call your healthcare provider if your symptoms do not improve, or if they get worse while using senna. Do not use this product for longer than 1 week without the advice of a healthcare provider.

What should I discuss with my health care provider before taking SenoSol-X (senna)?

Ask a doctor, pharmacist, herbalist, or other healthcare provider if it is safe for you to use this product if you have:

• 
  

  a bowel disorder such as Crohn's disease or ulcerative colitis;

  
  


• 
  

  heart disease; or

  
  


• 
  

  stomach pain, nausea, or vomiting.

  
  

Before using senna, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use senna if you have any other medical conditions, allergies, or if you take other medicines or herbal/health supplements.

Do not take senna without first talking to your doctor if you are pregnant or could become pregnant. Do not take senna without first talking to your doctor if you are breast-feeding a baby. Some forms of senna are made for use by children. Do not give any herbal/health supplement to a child without the advice of a doctor.

How should I take SenoSol-X (senna)?

When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.

If you choose to use senna, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.

Senna is usually taken before bed to produce a bowel movement 6 to 12 hours later when you wake up.

Do not use different forms (such as tablets and liquid) of senna at the same time unless your healthcare provider tells you to. Call your healthcare provider if your symptoms do not improve, or if they get worse while using senna. Do not use this product for longer than 1 week without the advice of a healthcare provider. Store senna at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking SenoSol-X (senna)?

Follow your healthcare provider's instructions about any restrictions on food, beverages, or activity.

SenoSol-X (senna) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your healthcare provider at once if you have a serious side effect such as:

• 
  

  severe stomach pain, severe diarrhea, watery diarrhea;

  
  


• 
  

  weight loss;

  
  


• 
  

  worsening constipation after you stop taking senna;

  
  


• 
  

  enlargement of your fingers and toes;

  
  


• 
  

  low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or

  
  


• 
  

  nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

  
  

Less serious side effects may include:

• 
  

  stomach cramps, bloating, gas, mild diarrhea;

  
  


• 
  

  numbness or tingly feeling;

  
  


• 
  

  joint pain; or

  
  


• 
  

  discolored urine.

  
  

This is not a complete list of side effects and others may occur. Tell your doctor, pharmacist, herbalist, or other healthcare provider about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect SenoSol-X (senna)?

Do not take senna without the advice of a healthcare provider if you are using any of the following medications:

• 
  

  digoxin (Lanoxin);

  
  


• 
  

  a diuretic (water pill); or

  
  


• 
  

  a blood thinner such as warfarin (Coumadin).

  
  

This list is not complete and other drugs may interact with senna. Tell your healthcare provider about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More SenoSol-X resources

• SenoSol-X Side Effects (in more detail)
• SenoSol-X Use in Pregnancy & Breastfeeding
• SenoSol-X Drug Interactions
• SenoSol-X Support Group
• 0 Reviews for SenoSol-X - Add your own review/rating

• Senna Natural MedFacts for Professionals (Wolters Kluwer)


• Senna Professional Patient Advice (Wolters Kluwer)


• Senna Natural MedFacts for Consumers (Wolters Kluwer)


• Senna Monograph (AHFS DI)


• Senexon Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• Senokot MedFacts Consumer Leaflet (Wolters Kluwer)

Compare SenoSol-X with other medications

• Bowel Preparation
• Constipation

Where can I get more information?

• Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.

See also: SenoSol-X side effects (in more detail)

Sensorcaine Solution

Pronunciation: byoo-PIV-a-kane
Generic Name: Bupivacaine
Brand Name: Examples include Marcaine and Sensorcaine

Sensorcaine Solution is used for:

Numbing (loss of feeling) during dental or surgical procedures, labor, or delivery. It may also be used for other conditions as determined by your doctor.

Sensorcaine Solution is a local anesthetic. It works by blocking the generation and conduction of nerve impulses.

Do NOT use Sensorcaine Solution if:

• you are allergic to any ingredient in Sensorcaine Solution or other similar medicines (eg, amide-type anesthetics)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Sensorcaine Solution:

Some medical conditions may interact with Sensorcaine Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have liver or kidney problems, heart disease, or blood pressure problems

Some MEDICINES MAY INTERACT with Sensorcaine Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, atenolol) or digoxin because the risk of side effects such as abnormal heartbeat may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Sensorcaine Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Sensorcaine Solution:

Use Sensorcaine Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Sensorcaine Solution will be administered as an injection at your doctor's office, hospital, or clinic.


• If you miss a dose of Sensorcaine Solution, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Sensorcaine Solution.

Important safety information:

• Sensorcaine Solution may cause drowsiness, dizziness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Sensorcaine Solution. Using Sensorcaine Solution alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• If you are going home before the numbness wears off, protect the treated area from injury until you regain feeling. If you received Sensorcaine Solution for a dental procedure, do not chew gum or eat until the feeling comes back. Also be careful not to bite your tongue or the inside of your mouth.


• Some of these products contain sulfites, which can cause allergic reactions in certain individuals (eg, asthma patients). If you have previously had allergic reactions to sulfites, contact your pharmacist to determine if the product you are taking contains sulfites.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Sensorcaine Solution during pregnancy. Sensorcaine Solution is excreted in breast milk. Do not breast-feed while taking Sensorcaine Solution.

Possible side effects of Sensorcaine Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild dizziness or drowsiness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; changes in hearing; chest pain; excitement; irregular heartbeat; nausea; numbness that lasts for more than a few hours; restlessness; ringing in the ears; seizures; severe dizziness or drowsiness; tremors; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Sensorcaine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include seizures; shortness of breath; slow heartbeat.

Proper storage of Sensorcaine Solution:

Store Sensorcaine Solution at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Sensorcaine Solution out of the reach of children and away from pets.

General information:

• If you have any questions about Sensorcaine Solution, please talk with your doctor, pharmacist, or other health care provider.


• Sensorcaine Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Sensorcaine Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Sensorcaine resources

• Sensorcaine Side Effects (in more detail)
• Sensorcaine Use in Pregnancy & Breastfeeding
• Sensorcaine Drug Interactions
• Sensorcaine Support Group
• 0 Reviews for Sensorcaine - Add your own review/rating

Compare Sensorcaine with other medications

• Cesarean Section
• Local Anesthesia

Septocaine

Generic Name: Articaine Hydrochloride
Class: Local Anesthetics
Chemical Name: 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiopenecarboxylic acid methyl ester monohydrochloride
Molecular Formula: C₁₃H₂₀N₂O₃S•HCl
CAS Number: 23964-57-0

Introduction

Intermediate-acting local anesthetic (amide type).^{1 2 3 4}

Uses for Septocaine

Dental Anesthesia

Local, infiltrative, or regional (i.e., nerve block) anesthesia in simple and complex dental and periodontal procedures.^{1 8}

Anesthetic activity comparable to that of lidocaine, mepivacaine, and prilocaine.^{2 4 7}

Septocaine Dosage and Administration

General

• 
  

  Determine dosage based on type and extent of surgical procedure, depth of anesthesia, degree of muscular relaxation, and condition of the patient.¹ Use smallest dose required to produce the desired effect.¹

  
  


• 
  

  For pediatric patients, determine dosage based on age, weight, physical condition of the patient, and type and extent of surgical procedure.¹

  
  

Administration

Submucosal Injection

For solution and drug compatibility information, see Compatibility under Stability.

Administer by submucosal infiltration or by nerve block.¹

Aspirate prior to administration to guard against intravascular injection.¹

For chemical disinfection of the cartridge unit, use isopropyl (rubbing) alcohol (91%) or ethyl alcohol (70%).¹ Do not use brands that are not of USP grade, since these preparations may contain denaturants that may be injurious to rubber.¹

Dosage

Available as fixed combination containing articaine hydrochloride and epinephrine bitartrate; dosage expressed in terms of articaine hydrochloride.¹

Pediatric Patients

Dental Anesthesia

Submucosal Injection

Children ≥4 years of age: Use lower dosages than those suggested for healthy adults (see Adults under Dosage and Administration).¹

Simple procedures: 0.76–5.65 mg/kg used in clinical trials.¹

Complex procedures: 0.37–7.48 mg/kg used in clinical trials.¹

Approximately 13% of pediatric patients in clinical trials required additional injections for complete anesthesia.¹

Adults

Dental Anesthesia

Submucosal Injection

Usual dosage range: 20–204 mg.¹

Recommended Dosages (as articaine hydrochloride 4% with epinephrine 1:100,000) for Dental Anesthesia in Healthy Adults1

Procedure	Volume of Injection (mL)	Total Dose of Articaine Hydrochloride (mg)
Infiltration	0.5–2.5	20–100
Nerve block	0.5–3.4	20–136
Oral surgery	1–5.1	40–204

Prescribing Limits

Pediatric Patients

Dental Anesthesia

Submucosal Injection

Maximum 7 mg/kg (0.175 mL/kg).¹

Adults

Dental Anesthesia

Submucosal Injection

Maximum 7 mg/kg (0.175 mL/kg).¹

Special Populations

Hepatic Impairment

Reduce dosage in patients with hepatic disease.¹

Geriatric Patients

Reduce dosage in patients ≥65 years of age.¹

Patients 65–74 Years of Age

Simple procedures: 0.43–4.76 mg/kg used in clinical trials.¹

Complex procedures: 1.05–4.27 mg/kg used in clinical trials.¹

Approximately 6% of patients in clinical trials required additional injections for complete anesthesia.¹

Patients ≥75 Years of Age

Simple procedures: 0.78–4.76 mg/kg used in clinical trials.¹

Complex procedures: 1.12–2.17 mg/kg used in clinical trials.¹

None of the patients in clinical trials required additional injections for complete anesthesia.¹

Other Populations

Reduce dosage in patients with cardiac disease, debilitated patients, and patients with acute illnesses.¹

Cautions for Septocaine

Contraindications

• 
  

  Known hypersensitivity to local anesthetics of the amide type or to sodium metabisulfite.^{1 4}

  
  

Warnings/Precautions

Warnings

Epinephrine Administration

Injection contains epinephrine, which may cause tissue necrosis or systemic toxicity.¹ Consider usual precautions associated with epinephrine administration.¹

Accidental Intravascular Injection

Accidental intravascular injection may result in confusion, seizures, CNS or cardiorespiratory depression, coma, and/or respiratory arrest.¹

Aspirate prior to administration to guard against intravascular injection.¹

Should be used only by clinicians who are sufficiently knowledgeable in the diagnosis and management of dose-related toxicity and other acute emergencies that might arise.¹ Resuscitative equipment and drugs must be available for immediate use.¹

Sensitivity Reactions

Sulfite Sensitivity

Articaine injection contains sodium metabisulfite, which may cause allergic-type reactions (including anaphylaxis and life-threatening or less severe asthmatic episodes) in certain susceptible individuals.¹

General Precautions

CNS Effects

Toxic plasma concentrations of local anesthetics (resulting from systemic absorption) associated with adverse CNS effects (e.g., restlessness, anxiety, tinnitus, lightheadedness, dizziness, disorientation, excitement, blurred vision, tremors, depression, drowsiness).^{1 3}

Carefully monitor level of consciousness after each local anesthetic injection.¹

Cardiovascular Effects

Toxic plasma concentrations of local anesthetics (resulting from systemic absorption) associated with adverse cardiovascular effects (e.g., reduced myocardial contractility, peripheral vasodilation, depressed cardiac conduction and excitability).¹ Possible atrioventricular block, ventricular arrhythmia, cardiac arrest, and, rarely, death.¹ Carefully monitor cardiovascular and respiratory vital signs after each local anesthetic injection.¹

Cardiac arrhythmias may occur in patients receiving potent general anesthetics; use with caution in such patients.¹

Articaine hydrochloride injection contains epinephrine; risk of exaggerated vasoconstrictor response in patients with hypertension or peripheral vascular disease.¹ Risk of ischemic injury or necrosis.¹

Use with caution in patients with heart block or other cardiovascular disease.¹

Specific Populations

Pregnancy

Category C.¹

Lactation

Not known whether articaine or its metabolites are distributed into milk.^{1 4} Caution advised if used in nursing women.¹

Pediatric Use

Safety and efficacy not established in children <4 years of age.^{1 4}

Geriatric Use

No substantial differences in safety and efficacy relative to younger adults, but increased sensitivity cannot be ruled out.¹

Hepatic Impairment

Not studied in patients with hepatic impairment.¹ Use with caution in patients with severe hepatic impairment.¹

Common Adverse Effects

Pain,^{1 2 4 7} headache,^{1 2 4 7} facial edema,^{1 2 4} gingivitis,^{1 2 4} paresthesia,^{1 2 4} infection.^{1 2 4}

Interactions for Septocaine

Approximately 5–10% of available articaine is metabolized by CYP enzymes.^{1 3}

Specific Drugs

Drug	Interaction	Comments
Anesthetics, general	Possible cardiac arrhythmias when articaine is administered during or following administration of potent general anesthetics1	Use with caution1
Antidepressants, tricyclics	Possible severe, prolonged hypertension due to epinephrine component1	Avoid concomitant use;1 if must be used concomitantly, careful monitoring is required1
Butyrophenones	Possible reduction or reversal of pressor effect of epinephrine1	Avoid concomitant use;1 if must be used concomitantly, careful monitoring is required 1
MAO inhibitors	Possible severe, prolonged hypertension due to epinephrine component1	Avoid concomitant use;1 if must be used concomitantly, careful monitoring is required1
Phenothiazines	Possible reduction or reversal of pressor effect of epinephrine1	Avoid concomitant use;1 if must be used concomitantly, careful monitoring is required1

Septocaine Pharmacokinetics

Absorption

Bioavailability

Peak plasma concentrations achieved approximately 25 minutes following single dose and 48 minutes following 3 doses.¹

Onset

1–6 minutes following submucosal injection.¹ Average onset of anesthesia following articaine administration appears to be similar to that of prilocaine^{5 6 8} but slightly faster than that of other local anesthetics (e.g., lidocaine).^{3 5 8}

Duration

Complete anesthesia lasts approximately 1 hour.¹

Distribution

Plasma Protein Binding

Approximately 60–80% (albumin and γ-globulins).¹

Elimination

Metabolism

Systemically absorbed articaine is rapidly metabolized by plasma carboxyesterase to articainic acid (inactive);¹ approximately 5–10% of available articaine is metabolized to articainic acid by CYP enzymes.^{1 3}

Elimination Route

Excreted principally in urine as inactive metabolites and small amounts (2%) of unchanged drug;^{1 4} approximately 53–57% of administered dose excreted within 24 hours following submucosal administration.¹

Half-life

Approximately 1.8 hours.¹

Stability

Storage

Parenteral

Injection

25°C (may be exposed to 15–30°C).¹ Protect from light.¹

Compatibility

For information on systemic interactions resulting from concomitant use, see Interactions.

May be incompatible with strong oxidizing agents.^a

ActionsActions

• 
  

  Local anesthetics block the generation and conduction of nerve impulses by increasing the threshold for electrical excitation, slowing the propagation of the nerve impulse, and reducing the rate of rise of the action potential.¹

  
  


• 
  

  Formulated with epinephrine to decrease articaine's rate and extent of systemic absorption and to prolong its duration of action.^{1 4}

  
  


• 
  

  Has intermediate duration of action (approximately 1 hour).^{1 2 3 4}

  
  

Advice to Patients

• 
  

  Prior to administration, advise patients of the possibility of temporary loss of sensation and muscle function following infiltration and nerve block injections.¹

  
  


• 
  

  Importance of informing clinicians of existing or contemplated therapy, including prescription and OTC drugs, as well as any concomitant illnesses (e.g., cardiovascular disease).¹

  
  


• 
  

  Importance of women informing their clinician if they are or plan to become pregnant or plan to breast-feed.¹

  
  


• 
  

  Importance of informing patients of other important precautionary information. (See Cautions.)

  
  

Preparations

Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.

Articaine Hydrochloride

Routes	Dosage Forms	Strengths	Brand Names	Manufacturer
Parenteral	Injection	4% with Epinephrine Bitartrate 1:100,000 (of epinephrine)	Septocaine (with sodium metabisulfite)	Septodont

Disclaimer

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. and Drugs.com represent that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. and Drugs.com make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. and Drugs.com do not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS Drug Information. © Copyright, 1959-2011, Selected Revisions May 2004. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.

References

1. Septodont, Inc. Septocaine (articaine hydrochloride 4% with epinephrine 1:100,000) injection prescribing information. New Castle, DE; 2000 Apr.

2. Malamed SF, Gagnon S, Leblanc D. Efficacy of articaine: a new amide local anesthetic. J Am Dent Assoc. 2000; 131:635-42. [IDIS 448169] [PubMed 10832257]

3. Oertel R, Rahn R, Kirch W. Clinical pharmacokinetics of articaine. Clin Pharmacokinet. 1997; 33:417-25. [PubMed 9435991]

4. Malamed SF, Gagnon S, Leblanc D. Articaine hydrochloride: a study of the safety of a new amide local anesthetic. J Am Dent Assoc. 2001; 132:177-85. [IDIS 466889] [PubMed 11217590]

5. Simon MAM, Gielen MJM, Alberink N et al. Intravenous regional anesthesia with 0.5% articaine, 0.5% lidocaine, or 0.5% prilocaine. Reg Anesth. 1997; 22:29-34. [PubMed 9010944]

6. Pitkanen MT, Xu M, Haasio J et al. Comparison of 0.5% articaine and 0.5% prilocaine in intravenous regional anesthesia of the arm: a cross-over study in volunteers. Reg Anesth Pain. 1999; 24:131-5.

7. Malamed SF, Gagnon S, Leblanc D et al. A comparison between articaine HCl and lidocaine HCl in pediatric dental patients. Pediatr Dent. 2000; 22:307-11. [PubMed 10969438]

8. Septodont Inc., New Castle, DE: Personal communication.

a. Septodont, Inc. Septocaine (articaine hydrochloride) injection material safety data sheet. New Castle, DE; 2002 Jul.

More Septocaine resources

• Septocaine Side Effects (in more detail)
• Septocaine Use in Pregnancy & Breastfeeding
• Septocaine Drug Interactions
• Septocaine Support Group
• 0 Reviews for Septocaine - Add your own review/rating

• Septocaine Prescribing Information (FDA)


• Septocaine Concise Consumer Information (Cerner Multum)

Compare Septocaine with other medications

• Anesthesia
• Local Anesthesia

Seromycin

Generic Name: cycloserine (sye kloe SER een)

Brand Names: Seromycin

What is Seromycin (cycloserine)?

Cycloserine is an antibiotic. It prevents tuberculous bacteria from growing in your body.

Cycloserine is used to treat tuberculosis (TB).

Cycloserine is also sometimes used to treat urinary tract and other types of infections that have not responded to other treatments.

Cycloserine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Seromycin (cycloserine)?

Take all of the cycloserine that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated. Avoid alcohol while taking cycloserine. Alcohol will increase your risk of having a seizure during cycloserine treatment. Alcohol will also increase dizziness and drowsiness. Use caution when driving, operating machinery, or performing other hazardous activities. Cycloserine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Call your doctor immediately if you experience a skin rash, mental confusion, dizziness, headache, or tremors (shaking).

Who should not take Seromycin (cycloserine)?

You cannot take cycloserine if you

• 
  

  have epilepsy,

  
  


• 
  

  suffer from depression,

  
  


• 
  

  have an anxiety disorder,

  
  


• 
  

  have a psychotic or psychiatric disorder,

  
  


• 
  

  have kidney disease, or

  
  


• 
  

  drink alcohol on a daily basis.

  
  

Cycloserine is in the FDA pregnancy category C. This means that it is not known whether cycloserine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant Cycloserine passes into breast milk, and it is not known whether cycloserine will harm a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take Seromycin (cycloserine)?

Take cycloserine exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass (8 ounces) of water.

Cycloserine is usually taken twice a day. Follow your doctor's instructions.

Take all of the cycloserine that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.

Cycloserine is usually combined with one or more other tuberculosis medicines.

Your doctor may also want you to take a supplemental vitamin B6 (pyridoxine) tablet daily during treatment to lessen side effects.

Store this medication at room temperature away from moisture and heat.

See also: Seromycin dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.

What should I avoid while taking Seromycin (cycloserine)?

Avoid alcohol while taking cycloserine. Alcohol will increase your risk of having a seizure during treatment with this medication. Also, alcohol will increase dizziness and drowsiness. Use caution when driving, operating machinery, or performing other hazardous activities. Cycloserine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Seromycin (cycloserine) side effects

If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

• 
  

  an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

  
  


• 
  

  seizures;

  
  


• 
  

  numbness or tingling in your hands or feet;

  
  


• 
  

  a skin rash;

  
  


• 
  

  confusion or abnormal behavior;

  
  


• 
  

  tremors (shaking);

  
  


• 
  

  headache;

  
  


• 
  

  drowsiness;

  
  


• 
  

  dizziness;

  
  


• 
  

  difficulty speaking; or

  
  


• 
  

  irritability.

  
  

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Seromycin (cycloserine)?

Before taking cycloserine, tell your doctor if you are taking

• 
  

  ethionamide (Trecator-SC), or

  
  


• 
  

  isoniazid (Nydrazid).

  
  

You may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with cycloserine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

More Seromycin resources

• Seromycin Side Effects (in more detail)
• Seromycin Dosage
• Seromycin Use in Pregnancy & Breastfeeding
• Seromycin Drug Interactions
• Seromycin Support Group
• 0 Reviews for Seromycin - Add your own review/rating

• Seromycin Monograph (AHFS DI)


• Seromycin MedFacts Consumer Leaflet (Wolters Kluwer)


• Seromycin Advanced Consumer (Micromedex) - Includes Dosage Information


• Seromycin Prescribing Information (FDA)


• Cycloserine


• Cycloserine Professional Patient Advice (Wolters Kluwer)

Compare Seromycin with other medications

• Tuberculosis, Active
• Tuberculosis, Extrapulmonary

Where can I get more information?

• Your pharmacist has additional information about cycloserine written for health professionals that you may read.

See also: Seromycin side effects (in more detail)

Sentry SA Dritail

Dosage Form: FOR ANIMAL USE ONLY
Treatment for Diarrhea ("Wet Tail")

Indications and Usage for Sentry SA Dritail

SYMPTOMS:     

• Diarrhea


• Wet or matted tail


• Dehydration


• Obvious changes in appearance or behavior
  

Concentrated formula

Easily administered in water

Designed to appeal to small animals' tastes

Treats symptoms in hamsters, gerbils, mice, rats , and guinea pigs.

DOSAGE & ADMINISTRATION

Treat animal with full recommended dosage.  Discontinue feeding greens and roughage to animals that have diarrhea.  Treat for a minimum of 5 days.  Repeat the treatment if necessary.  If condition persists and no improvement is noted during treatment, consult your veterinarian.  Sick animals should be separated from healthy animals.  If more than one animal is caged together, all animals should be treated for a period of 5 days to prevent infection.


Oral Dropper Method (for hamsters and guinea pigs only):

Weigh your pet and use the weight chart to determine the amount of DriTail to use.  Young animals (six months old or less) should be given 1/2 the recommended adult dosage.  Allow the animal to lap medicine from the dropper; be careful not to force medicine into the mouth faster than your pet can lap it up.

Common Name	Weight	Amount of DriTail
Siberian Hamster	25-35g (1 oz)	1/4 mL (8 drops) once daily
Chinese Hamster	30-50g (1 1/2 oz)	1/4 mL (8 drops) once daily
Golden Hamster	110-140g (4-5 oz)	1/2 mL (16 drops) once daily
Guinea Pig	800-1200g (2-2 1/2 lbs)	3/4 mL (24 drops) once daily

Oral Drinking Water Method (gerbils, mice, rats, hamsters, guinea pigs):

Add 3 teaspoons (15 mL) of DriTail to 4 oz. (120 mL) of water.  The water should be changed daily and should be your pet's only source of water. 

Precautions

Do not use for nonrodents such as rabbits.  For pet animal use only.

KEEP OUT OF REACH OF CHILDREN

ACTIVE INGREDIENT

Neomycin sulfate equivalent to not less than 20 mg/mL of neomycin base.

How is Sentry SA Dritail Supplied

Net Contents:


1 fl. oz. (29.5 mL) Dropper


16 fl. oz. (473 mL)

PACKAGE LABEL PRINCIPLE DISPLAY PANEL

Distributed by:


Sergeant's Pet Care Products, Inc., Omaha NE 68130


Made in USA


www.sentrypetcare.com

Sentry SA Dritail  neomycin sulfate  liquid

Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 21091-932 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength NEOMYCIN SULFATE (NEOMYCIN) NEOMYCIN SULFATE 20 mg  in 1 mL

Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 21091-932-01 1 BOTTLE In 1 BLISTER PACK contains a BOTTLE, PLASTIC 1 29.5 mL In 1 BOTTLE, PLASTIC This package is contained within the BLISTER PACK (21091-932-01) 2 21091-932-16 473 mL In 1 BOTTLE, PLASTIC None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
unapproved drug other		12/08/2008

Labeler - Sergeant's Pet Care Products, Inc. (876995171)

Revised: 12/2009Sergeant's Pet Care Products, Inc.